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Yesterday's no could be an enrollee tomorrow. If you know why.

Overstand connects the reasons medically-qualified patients say no — captured in coordinator notes, emails, and call logs — with new protocols where those barriers no longer apply.

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Backed by Y Combinator

Recruitment context is lost between studies.

Clinical trial recruitment treats every protocol as a fresh start. Screen failures are filed away, coordinator notes stay in personal notebooks, and patients who expressed interest in future studies are never re-contacted. The result: sites recruit from zero every time.

Patient #2,847

Declined

"Visit schedule conflicts with caregiving — interested if fewer on-site visits"

Coordinator note: "Single parent, school pickup at 3pm, all visits currently 2-4pm"

Patient #2,848

Declined

"Travel distance too far — 90min each way by bus"

Coordinator note: "Asked about satellite sites, very motivated"

Patient #2,849

Declined

"Uncomfortable with randomization to placebo arm"

Coordinator note: "Would enroll in single-arm or open-label study"

Patient Emails
Call Notes
Screening Records
Coordinator Notes
Protocol Databases
Intake Forms

Recruitment data is scattered across systems — screening databases, coordinator notebooks, patient emails, call logs, protocol files, and intake forms. The insights that could accelerate the next study are invisible when each source is siloed.

Every new protocol means starting from scratch — re-screening patients you've already evaluated, re-learning which barriers are transient, and losing the coordinator knowledge that took months to build. Outcomes are recorded, but the reasoning behind them disappears.

Turn screening history into a recruitment advantage.

Overstand builds institutional memory across your clinical trials — connecting what you know about patients to what new studies need.

Unify Screening Data and Communication

  • Screening records, coordinator notes, patient emails, call logs, and lab data — unified automatically
  • Cross-study context preserved — coordinator insights from one protocol carry forward to the next
  • Works with the screening data you already have — no new collection required
Screenings
Eligibility
Lab Data
Emails
Call Notes
Coord. Notes

Unified Patient Intelligence

6 sources connected

Live
Screening outcomes linked to coordinator context
Cross-study patient matching active across 6 protocols
142 re-eligible patients identified from prior studies
850+ screening records unified across protocols

Surface Prior Context for New Studies

When a new protocol opens, Overstand identifies patients from prior studies whose circumstances have changed — re-contactable before you start cold outreach.

What sites see today
BEACON-3 · Sep 12 Declined

"Weekly visits conflict with work schedule"

BEACON-3 · Aug 28 Declined

"Travel distance — 90 min by public transit"

SUMMIT-1 · Jun 22 Declined

"Concerned about randomization to placebo"

PINNACLE-2 · Mar 15 Declined

"Caregiver unavailable for infusion days"

What Overstand sees

4 Re-contactable Patients Found

HORIZON-1
  • Work schedule resolved — patient changed jobs; now available weekdays. Coordinator note flagged interest in future studies
  • New satellite site open 15 min from patient's home — previously declined for travel
  • HORIZON-1 is single-arm, open-label — patient previously declined randomized study
  • Spouse retired — caregiver now available. Patient emailed asking about new openings
Matched across 3 prior studies using coordinator notes, patient emails, and intake forms

Let Patterns Compound Across Protocols

Every study teaches you something about your patient population. Overstand ensures those lessons are never lost.

Barrier Resolution Detection

Identify when non-medical barriers have resolved — a patient who moved closer, changed jobs, or gained caregiver support — and flag them for re-contact.

Cross-Study Matching

When new protocols open, match study design features (visit frequency, administration method, randomization) against patient preferences documented in prior communications.

Recruitment Pattern Analysis

Learn which non-medical factors drive the most declines — travel, scheduling, study design concerns — and how protocol adjustments can recover those patients.

Built for Sensitive Patient Data

Infrastructure designed to protect patient information at every layer.

HIPAA-Ready

Infrastructure designed to meet HIPAA requirements for protected health information.

Encrypted End-to-End

Patient data encrypted at rest and in transit.

Role-Based Access

Granular permissions — coordinators, PIs, and sponsors see only what they need.

Frequently Asked Questions

Common questions about clinical trial recruitment intelligence, screening data integration, and cross-study patient matching.

Overstand is more than a clinical trial tool. Find out what else Overstand can do for you on our home page.

Ready to see Overstand in action?

Schedule a demo to see how Overstand can make the data you already have work for you.